Isocitrate Dehydrogenase Mitochondrial (ICDHm) Assay Kit

Isocitrate Dehydrogenase Mitochondrial (ICDHm) Assay Kit

Mitochondrial Isocitrate Dehydrogenase (ICDHm, EC 1.1.1.41) is widely present in the mitochondria of animals, plants, microorganisms, and cultured cells. In the tricarboxylic acid cycle, it catalyzes the conversion of isocitrate to α-ketoglutarate while reducing nicotinamide adenine dinucleotide (oxidized form, NAD⁺) to nicotinamide adenine dinucleotide (reduced form, NADH). It is one of the rate-limiting enzymes of the tricarboxylic acid cycle, and the reaction it catalyzes is one of the main sources of cellular NADH.

ICDHm catalyzes the reduction of NAD⁺ to generate NADH, which leads to an increase in light absorption at 340 nm. The activity of ICDHm can be determined by measuring the rate of this absorbance increase.

1. This product is for scientific research use only. Please do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Please not store it in a general residential area.

2. For your safety and health, please wear a lab coat and disposable gloves and masks when operating.

3. The experimental can be affected by a variety of factors, and the relevant treatment is limited to the product itself, and does not involve other compensation.