△Alf1 Yeast strain

△Alf1 Yeast strain

Alf1 is a tubulin-specific chaperone B, functioning similarly to mammalian cofactor B. It is localized on cytoplasmic microtubules and primarily assists in the proper folding of α-tubulin, participating in the "post-chaperonin tubulin folding pathway." The ALF1 gene and its mutants serve as an ideal model for studying the interplay between cytoskeletal dynamics and genomic stability.

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