Y8800 Yeast strain

Y8800 Yeast strain

Y8800 is a haploid Saccharomyces cerevisiae strain widely used for CrY2H screening. This strain incorporates a triple reporter system integrating three genes—HIS3 (for histidine-based nutritional screening), ADE2 (for adenine-based nutrition and red coloration), and lacZ (for β-galactosidase coloration)—effectively reducing false positives. It is commonly paired with the MATα strain Y8930. Its genotype is: MATa leu2-3,112 trp1-901 his3-200 ura3-52 gal4∆ gal80∆ PGAL2-ADE2 LYS2::PGAL1-HIS3 MET2::PGAL7-lacZ cyh2R.

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